Shigeki Hirano Selected Research

N-methylpiperidin-4-yl acetate

7/2010

Cholinergic imaging in corticobasal syndrome, progressive supranuclear palsy and frontotemporal dementia.

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Shigeki Hirano Research Topics

Disease

15	Parkinson Disease (Parkinson's Disease) 03/2022 - 04/2008
12	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 12/2005
5	Multiple System Atrophy 12/2022 - 01/2009
5	Cognitive Dysfunction 01/2022 - 10/2012
4	Dyskinesias (Dyskinesia) 03/2022 - 10/2019
4	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 01/2022 - 01/2009
4	Dementia (Dementias) 01/2021 - 10/2012
3	Parkinsonian Disorders (Parkinsonism) 01/2022 - 05/2010
3	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2019 - 04/2008
2	Corticobasal Degeneration 01/2022 - 07/2010
2	Atrophy 08/2019 - 02/2013
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2019 - 01/2018
2	Pain (Aches) 10/2018 - 11/2012
2	Neoplasms (Cancer) 08/2018 - 10/2010
2	Major Depressive Disorder (Major Depressive Disorders) 01/2017 - 01/2013
2	Ataxia (Dyssynergia) 07/2013 - 06/2008
2	Tremor (Tremors) 01/2011 - 04/2010
1	Hypoventilation 12/2022
1	Hypercapnia 12/2022
1	Machado-Joseph Disease (Spinocerebellar Ataxia Type 3) 04/2020
1	Orthostatic Hypotension (Postural Hypotension) 04/2020
1	Hallucinations (Hallucination) 01/2020
1	Constipation 01/2020
1	Deglutition Disorders (Dysphagia) 01/2020
1	Movement Disorders (Movement Disorder) 01/2020
1	Neuralgia (Stump Neuralgia) 10/2018
1	Dyspnea (Shortness of Breath) 08/2018
1	Neuroinflammatory Diseases 01/2018
1	Hypothermia 01/2018
1	Pulmonary Embolism 01/2018
1	Chorea (Rheumatic Chorea) 01/2018
1	Tauopathies 01/2017
1	Amyloid Plaque 06/2014
1	POEMS Syndrome (Syndrome, POEMS) 12/2013
1	Lewy Body Disease (Lewy Body Dementia) 02/2013
1	Sleepiness 01/2013
1	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 01/2013
1	Nausea 01/2013
1	Hyperglycemia 12/2012
1	Atherosclerosis 12/2012
1	Hypoglycemia (Reactive Hypoglycemia) 12/2012
1	Chronic Pain 11/2012
1	Disruptive, Impulse Control, and Conduct Disorders (Kleptomania) 10/2012
1	Frontotemporal Dementia (Semantic Dementia) 07/2010
1	Essential Tremor (Essential Tremors) 04/2010
1	Neurobehavioral Manifestations 01/2009
1	Acute Disseminated Encephalomyelitis (Postinfectious Encephalomyelitis) 10/2008

Drug/Important Bio-Agent (IBA)

8	Amyloid (Amyloid Fibrils)IBA 01/2022 - 10/2012
7	Cholinergic Agents (Cholinergics)IBA 01/2021 - 06/2008
6	AcetylcholinesteraseIBA 01/2018 - 12/2005
4	Levodopa (L Dopa)FDA LinkGeneric 03/2022 - 04/2008
4	Biomarkers (Surrogate Marker)IBA 06/2021 - 01/2009
3	Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA 01/2022 - 04/2010
2	Inosine Monophosphate (IMP)IBA 01/2022 - 10/2018
2	Dopamine (Intropin)FDA LinkGeneric 06/2020 - 10/2012
2	benzothiazoleIBA 01/2019 - 01/2017
2	Duloxetine Hydrochloride (Cymbalta)FDA Link 10/2018 - 01/2013
2	Proteins (Proteins, Gene)FDA Link 01/2018 - 12/2013
2	2- (4'- (methylamino)phenyl)- 6- hydroxybenzothiazole (Pittsburgh compound B)IBA 01/2017 - 02/2012
2	Donepezil (Aricept)FDA LinkGeneric 03/2010 - 12/2005
1	Carbon DioxideIBA 12/2022
1	istradefyllineIBA 03/2022
1	2- carbomethoxy- 8- (3- fluoropropyl)- 3- (4- iodophenyl)tropaneIBA 01/2022
1	Biological ProductsIBA 01/2022
1	Glucosylceramidase (Glucocerebrosidase)IBA 01/2021
1	Dopamine Receptors (Dopamine Receptor)IBA 06/2020
1	Monoamine Oxidase (MAO)IBA 06/2020
1	Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA 06/2020
1	Hexachlorobenzene (HCB)IBA 04/2020
1	hydroxide ionIBA 04/2020
1	Pharmaceutical PreparationsIBA 08/2019
1	LigandsIBA 01/2019
1	AutoantibodiesIBA 12/2018
1	Proteasome Endopeptidase Complex (Proteasome)IBA 12/2018
1	Opioid Analgesics (Opioids)IBA 08/2018
1	Oxycodone (Oxycontin)FDA LinkGeneric 08/2018
1	Escitalopram FDA Link 01/2017
1	Paroxetine (Paxil)FDA LinkGeneric 01/2017
1	CatecholaminesIBA 01/2015
1	AminesIBA 06/2014
1	Monoclonal AntibodiesIBA 12/2013
1	CytokinesIBA 12/2013
1	Bevacizumab (Avastin)FDA Link 12/2013
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2013
1	AntibodiesIBA 07/2013
1	Glucose (Dextrose)FDA LinkGeneric 06/2013
1	Mirtazapine (Rexer)FDA LinkGeneric 01/2013
1	DNA-Binding Proteins (DNA Binding Protein)IBA 01/2013
1	Insulin (Novolin)FDA Link 12/2012
1	thymidine 3',5'-diphosphate (pdTp)IBA 01/2011
1	N-methylpiperidin-4-yl acetateIBA 07/2010
1	technetium Tc 99m bicisate (Neurolite)FDA Link 04/2010
1	Acetates (Acetic Acid Esters)FDA Link 03/2010

Therapy/Procedure

9	Deep Brain Stimulation 01/2021 - 01/2011
9	Therapeutics 06/2020 - 04/2008
1	Duration of Therapy 08/2019
1	Aftercare (After-Treatment) 10/2018
1	Palliative Care (Palliative Therapy) 08/2018
1	Endarterectomy (Thromboendarterectomy) 01/2018
1	Drug Therapy (Chemotherapy) 10/2010